Shri Khare has held various assignments in both, Central & State Governments. He was Collector/Dy. Commissioner of 4 districts namely Darbhanga, Begusarai, West Singhbhum (Chaibasa) and Patna. He is noted for his role in bringing to light the infamous ‘Fodder Scam’ of Bihar in 1996 as the then Deputy Commissioner of West Singhbhum (Chaibasa).

He has long years of experience in Finance as also in the field of Education. He was Secretary, Board of Revenue, Bihar, the first Commissioner of Commercial Taxes of Jharkhand, Additional Finance Commissioner, Jharkhand and Principal Secretary and Additional Chief Secretary, Finance & Planning Department, Jharkhand. He also served as Secretary, Human Resource Development, Secretary Information & Public Relations Department, Jharkhand and Principal Secretary to Governor, Jharkhand as also Vice Chancellor of Ranchi University.

Shri Khare served the Central Government for 6 years as Joint Secretary, Higher Education from August 2008 to August 2014 looking after UNESCO, Education Policy and Book Promotion & Copyrights. He also served as Member Secretary of National Pharmaceutical Pricing Authority from September 2014 to April 2015. On return from central deputation, he served as Principal Secretary/ ACS, Finance-cum- Planning Deopartment and Development Commissioner of Jharkhand from April 2015 to May2018.

As Development Commissioner & ACS Finance-cum Planning, he took many initiatives for introducing wide spread pre- budget consultations, performance budgeting, gender budgeting & sectoral budgeting, financial inclusion, DBT and in implementation of various Central and State sector schemes.

He took over as Secretary, I&B, Government of India on 31st May 2018.